Patient-reported outcomes in patients with severe maxillary bone atrophy restored with zygomatic implant-supported complete dental prostheses: a systematic review.

Introduction and Objective: Zygomatic implants (ZI) offer a good and predictable alternative to reconstructive procedures of atrophic maxillae. The main objetive of this systematic review was to assess the effect of rehabilitation with zygomatic implants on patient's quality of life (QLP) using Patient Reported Outcomes Measures (PROMs).Materials and Methods: This review followed PRISMA guidelines. An automated electronic search was conducted in four databases supplemented by a manual search for relevant articles published until the end of January 2021. The Cochrane Collaboration Risk of Bias tool and the Newcastle-Ottawa Quality Assessment Scale were used to assess the quality of evidence in the studies reviewed.Results: General findings of this systematic review showed substantial increases in Oral health-related quality of life (OHRQoL) among patients restored with ZI and high scores in terms of general satisfaction, especially in chewing ability and esthetics. An overall survival rate of ZI was 98.3% after a mean follow-up time of 46.5 months was observed. Occurrence of 13.1% biological complications and 1.8% technical complications were reported.Conclusions: Patients rehabilitated with zygomatic implant-supported complete dental prostheses showed substantial improvements in OHRQoL and general satisfaction with the treatment received.

Effects of locally applied Insulin-like Growth Factor-I on osseointegration

Background: The aim of this study was to assess the effect of local application of IGF-I on osseointegration of dental implants placed in osteoporotic bones. Material and Methods: 16 rabbits were randomly distributed into two groups: eight animals were ovariectomized and fed a low-calcium diet for six weeks, in order to induce experimental osteoporosis, and the others were sham-operated and fed a standard diet. A titanium implant was inserted into the tibiae in both groups. In half of the rabbits, 4 μg of IGF-I was applied into the ostectomy, prior to the implant insertion. A total of 32 implants were placed. Animals were sacrificed two weeks after surgery and decalcified samples were processed for Bone-To-Implant Contact (BIC) and Bone Area Density (BAD) measurements. Analysis of variance (ANOVA) was used for statistical evaluation. P < 0.05 was considered to be significant. Results: Ovariectomy induced statistically significant lower BAD values (p = 0.008) and a tendency towards lower BIC values when compared osteoporotic and healthy groups. The administration of 4 μg of IGF-I did not produce statistically significant differences neither on BIC nor on BAD values, neither in the osteoporotic animals nor in healthy. Conclusions: Within the limitations of this experimental study, local administration of 4 μg of IGF-I was not able to induce any changes in the osseointegration process two weeks after surgery, neither in healthy rabbits nor in the osteoporotic group

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Tratamiento del tumor odontogénico queratoquístico: revisión sistemática / Surgical treatment of odontogenic keratocystic tumor: a systematic review

Introducción: El queratoquiste odontogénico (QO) se considera hoy en día un tumor odontogénico benigno. A pesar de esto, tiene un carácter agresivo debido fundamentalmente a su potencial expansivo a nivel local y a su alta capacidad de recidiva. Actualmente, existen diferentes variedades terapéuticas que se relacionan directamente con las tasas de recurrencia de este tipo de tumor. Objetivo: El objetivo de este estudio es analizar las tasas de recurrencia de las diferentes modalidades de tratamiento del QO. Material y método: Siguiendo las recomendaciones PRISMA se realizó una revisión sistemática en diferentes bases de datos analizando las tasas de recurrencia de distintas opciones terapéuticas del QO. Resultados: El porcentaje medio de recurrencia de los 11 artículos revisados fue del 26,8 %, siendo la resección en bloque el tratamiento con menores tasas de recidiva (0 %) y la marsupialización el tratamiento que mayor porcentaje de recurrencia presentó (45,8 %). Discusión: La recidiva se relaciona directamente con la posibilidad de que restos del tumor o del epitelio que lo rodea puedan permanecer en la cavidad después del tratamiento. Por ello, la resección en bloque es el tratamiento que menos recurrencia presenta. Sin embargo, la agresividad de esta modalidad terapéutica no está justificada en todos los casos, existiendo otras variantes muy eficaces como la enucleación, ya sea sola o en combinación con terapias coadyuvantes como la aplicación de solución de Carnoy. Conclusiones: El tratamiento resectivo presenta las menores tasas de recurrencia, aunque se considera que el QO puede ser abordado de una manera más conservadora dada su naturaleza benigna

Introduction: The odontogenic keratocystic (OK) is considered nowadays as a benign odontogenic tumor. Nevertheless, it has an aggressive nature due mainly to its local expansive potential and its high recurrence rate. Currently, there are different therapeutic approaches that are directly related to the recurrence rates of this type of tumor. Objective: The objective of this study is to analyze the recurrence rates of the different treatment modalities of the OK. Material and method: Following PRISMA recommendations, it was perfomed a systematic review in different databases analyzing the recurrence rates of different therapeutic options of the OK. Results: The average percentage of recurrence of the 11 articles reviewed was of 26,8 %, being resection the treatment with lower recurrence rates (0 %) and marsupialization the treatment with the highest percentage of recurrence (45,8 %). Discussion: Recurrence is directly related to the possibility that parts of the epithelium may remain in the cavity after treatment. Therefore, resection is the treatment with the least recurrence. However, the aggressiveness of this therapeutic modality is not justified in all cases. There are other very effective variants such as enucleation either alone or in combination with adjuvant therapies such as Carnoy's solution application. Conclusions: Resective treatment has the lowest recurrence rates although it is considered that the OK can be approached in a more conservative way due to its benign nature